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RNF130 Regulates LDLR Availability and Plasma LDL Cholesterol Levels.
Clifford BL, Jarrett KE, Cheng J, Cheng A, Seldin M, Morand P, Lee R, Chen M, Baldan A, de Aguiar Vallim TQ, Tarling EJ. Clifford BL, et al. Circ Res. 2023 Mar 31;132(7):849-863. doi: 10.1161/CIRCRESAHA.122.321938. Epub 2023 Mar 6. Circ Res. 2023. PMID: 36876496 Free PMC article.
Increasing the availability of hepatic LDL receptors (LDLRs) remains a major clinical target for reducing LDL-C levels. Here, we describe a novel role for RNF130 (ring finger containing protein 130) in regulating plasma membrane availability of …
Increasing the availability of hepatic LDL receptors (LDLRs) remains a major clinical target for reducing LDL-C levels. Here, we describe a …
RNF130 protects against pulmonary fibrosis through suppressing aerobic glycolysis by mediating c-myc ubiquitination.
Zhang J, Chen W, Du J, Chu L, Zhou Z, Zhong W, Liu D, Huang H, Huang Y, Qiao Y, Meng X, Zou F, Cai S, Dong H. Zhang J, et al. Int Immunopharmacol. 2023 Apr;117:109985. doi: 10.1016/j.intimp.2023.109985. Epub 2023 Mar 7. Int Immunopharmacol. 2023. PMID: 36893517 Free article.
Ring finger protein 130 (RNF130), was demonstrated involved in multiple diseases. ...Mechanistically, we revealed that RNF130 promotedc-myc ubiquitination and degradation, while c-myc overexpression reverses the inhibitory effects of R …
Ring finger protein 130 (RNF130), was demonstrated involved in multiple diseases. ...Mechanistically, we …